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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC6
All Species:
30.61
Human Site:
S381
Identified Species:
51.79
UniProt:
Q99741
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99741
NP_001245.1
560
62720
S381
Q
F
C
A
R
K
V
S
A
V
S
G
D
V
R
Chimpanzee
Pan troglodytes
XP_001170406
560
62717
S381
Q
F
C
A
R
K
V
S
A
V
S
G
D
V
R
Rhesus Macaque
Macaca mulatta
XP_001096756
559
62520
S381
Q
F
C
A
R
K
V
S
A
V
S
G
D
V
R
Dog
Lupus familis
XP_537648
559
62507
S380
Q
F
C
A
R
K
V
S
A
L
S
G
D
V
R
Cat
Felis silvestris
Mouse
Mus musculus
O89033
562
62595
S383
Q
F
C
A
R
K
V
S
A
V
S
G
D
I
R
Rat
Rattus norvegicus
NP_001101768
561
62295
S382
Q
F
C
A
R
K
V
S
A
V
S
G
D
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519126
361
39672
L201
I
V
L
N
C
M
S
L
R
S
S
Q
A
V
F
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001081844
554
60731
S373
Q
F
C
A
R
K
I
S
A
V
S
G
D
A
R
Zebra Danio
Brachydanio rerio
NP_001120805
561
61262
A380
G
E
G
V
L
D
A
A
A
V
Q
F
C
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648247
662
75116
S473
Q
L
L
A
A
K
V
S
A
I
S
G
D
V
R
Honey Bee
Apis mellifera
XP_625142
549
62089
A370
H
M
L
S
G
K
V
A
A
V
S
G
D
I
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999666
582
64455
A376
Q
L
C
A
R
K
V
A
A
V
A
G
D
V
R
Poplar Tree
Populus trichocarpa
XP_002299817
498
55546
G338
R
K
V
A
A
A
S
G
D
M
R
K
A
L
C
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P09119
513
58018
L353
E
L
E
K
R
F
L
L
S
P
T
R
G
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96
89.1
N.A.
79.5
80
N.A.
45.3
N.A.
63.7
49
N.A.
33.9
36
N.A.
40
Protein Similarity:
100
100
97.5
93.5
N.A.
87.3
88.9
N.A.
52.8
N.A.
77.5
67.3
N.A.
52.1
57.3
N.A.
58.5
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
13.3
N.A.
86.6
20
N.A.
73.3
53.3
N.A.
80
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
N.A.
93.3
26.6
N.A.
80
73.3
N.A.
93.3
Percent
Protein Identity:
25.8
N.A.
N.A.
N.A.
20.1
N.A.
Protein Similarity:
46.4
N.A.
N.A.
N.A.
41.2
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
72
15
8
8
22
79
0
8
0
15
15
0
% A
% Cys:
0
0
58
0
8
0
0
0
0
0
0
0
8
0
8
% C
% Asp:
0
0
0
0
0
8
0
0
8
0
0
0
72
0
0
% D
% Glu:
8
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
50
0
0
0
8
0
0
0
0
0
8
0
0
8
% F
% Gly:
8
0
8
0
8
0
0
8
0
0
0
72
8
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
8
0
0
8
0
0
0
22
0
% I
% Lys:
0
8
0
8
0
72
0
0
0
0
0
8
0
0
0
% K
% Leu:
0
22
22
0
8
0
8
15
0
8
0
0
0
8
8
% L
% Met:
0
8
0
0
0
8
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
65
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% Q
% Arg:
8
0
0
0
65
0
0
0
8
0
8
8
0
0
79
% R
% Ser:
0
0
0
8
0
0
15
58
8
8
72
0
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% T
% Val:
0
8
8
8
0
0
65
0
0
65
0
0
0
50
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _